EPR效应在动物模型上体现比较明显，但是在实际人体临床应用中没有太好的表现！
参考：To exploit the tumor microenvironment: since the EPR effect fails in the clinic, what is the future of nanomedicine. J Control Release. 2016 Dec 28;244(Pt A):108-121. doi: 10.1016/j.jconrel.2016.11.015. Epub 2016 Nov 18
